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There May Be A Research Study For You

Biomarkers of Nicotine Addiction:
Developing a Test of Nicotine Dependence

Study # 485-tx

What is the purpose of the research study?
To develop new ways to measure nicotine dependence severity that may be useful in predicting success in smoking cessation and in development of new smoking cessation treatment targets.

Who can participate in the study?
This study is accepting men and women who

  • Are 18 to 55 years of age
  • Are in generally good health
  • Are currently smoking and want to quit

What will participants be asked to do?

  • Attend 16 visits over 1 year
    • 1 session for consent, orientation and training, lasting about 3–4 hours
    • 6 MRI scans, total visit length is about 5 ½–6 ½ hours each
    • 12 weekly counseling (treatment) sessions, lasting about 1 hour each
  • Use e-cigarettes as nicotine replacement
  • Stop using all nicotine products for 2 days early in the study
  • Make a quit attempt and stop using all nicotine products for at least 1 year
  • 4 blood draws to obtain genetic and nicotine information
  • Brief medical assessment at each visit
  • Answer questionnaires about how you think and feel at each visit
  • Complete various thinking tasks inside and outside of the MRI

Where is the study taking place?
The NIDA Intramural Research Program is located on the Johns Hopkins Bayview campus in east Baltimore.

Will there be any cost to participate?
There is no cost for participation.

Will participants receive payment of some kind?
All study participants will be paid for their time and travel.

How can I find out if I’m eligible to participate?
Call 1-888-OUR-BRAIN (1-888-687-2724) for a confidential screening.